N Radjaee-Behbahani

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1. Methoxamine 0.5 microns induced an extremely regular rhythmic activity in isolated rabbit anococcygeus muscle. 2. Prazosin had an inhibitory effect on methoxamine-induced rhythmic contractions. IC50 of prazosin was 7.94 nM. 3. The methoxamine-induced contractions are dependent on extracellular calcium and can be inhibited by the omission of calcium from(More)
1. Clonidine 0.5 mM induced an extremely regular rhythmic activity in isolated rabbit anococcygeus muscle. The movements were resistant to tetrodotoxin effect. 2. Prazosin (5 x 10(-8)M-5 x 10(-6)M) and yohimbine (1.5 x 10(-7)M-5 x 10(-4)M) showed no remarkable effect on clonidine-induced rhythmic activity. 3. The clonidine-induced contractions were(More)
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