N. R. Teodósio

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The nutritional potentiality of the "Regional Basic Diet" (RBD) was assessed in albino rats. The diet, which was prepared according to data from food consumption surveys and was similar--in terms of quality and quantity--to those consumed by human populations in Northeast Brazil, was compared to a balanced diet (22% casein). The centesimal composition,(More)
The effects of aging on spreading depression (SD) were investigated in the Mongolian gerbil (G; age range 1.5 to 58 months; N = 35) and in albino rat (R; 2.5 to 24 months; N = 100). Two strains of rats were studied: Wistar (W; N = 35) and Sprague-Dawley (SDAW; N = 65). SDAW rats were divided into two groups: one group was fed a commercial lab chow diet (CD)(More)
Acute dehydration (D) early in life made adult rats less susceptible to cortical spreading depression (SD) than control (C) rats. Post weaning undernourished (U) rats tended to be more susceptible than controls. The association of D and U (DU group) made rats more susceptible to SD than U-rats. It is suggested that this association gives rise to a more(More)
The enhanced propagation rate of cortical spreading depression, observed previously in rats rendered malnourished by the regional basic diet that is typical of the daily fare of many of the inhabitants of the northeastern region of Brazil, was not prevented by raising the quantity of dietary protein to the normal level without changing its quality. Dietary(More)
1. Rats were fed the "basic regional diet" (BRD) utilized by some human populations in northeastern Brazil, which contains only 7.8% protein (mainly from beans), to produce a form of malnutrition. The effects of chronic malnutrition on nerve impulse conduction velocity was studied in the sciatic nerve of young (121-143 days) and old (420-540 days) rats. 2.(More)
Intestinal protein absorption was studied in undernourished albino Swiss mice with acute schistosomiasis mansoni. Undernutrition was induced by feeding mice with the Regional Basic Diet (RBD) ingested by human populations in Northeast Brazil, an experimental model previously developed in our laboratory. Weaning mice were infected with 40 cercariae and(More)
Depending on its intensity and duration, nutritional deficiency can disrupt the structure and function of the nervous system of humans and other mammals, with consequences more or less devastating for the whole organism, particularly in the early postnatal life, when body growth is very rapid and the need for proteins, calories and other nutrients is(More)
Two animal models of infantile malnutrition were produced where some aspects of carbohydrate metabolism can be studied: protein-depleted (PD, "kwashiorkor") rats, fed a protein-free diet for 18 days, starting 3 days before weaning, and chronically malnourished animals during suckling (PED, "marasmus") where 20-22 pups were fed by the same dam. PED and PD(More)
The cumulative effects of the long-term consumption of the Regional Basic Diet (RBD) of Northeast Brazil on gestational and lactational performances were assessed in three consecutive generations of Sprague Dawley rats (n = 1,334). The animals were distributed into three groups: RBD (8% predominantly vegetable-based proteins), Control (8% casein) and(More)