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The effects of aging on spreading depression (SD) were investigated in the Mongolian gerbil (G; age range 1.5 to 58 months; N = 35) and in albino rat (R; 2.5 to 24 months; N = 100). Two strains of rats were studied: Wistar (W; N = 35) and Sprague-Dawley (SDAW; N = 65). SDAW rats were divided into two groups: one group was fed a commercial lab chow diet (CD)(More)
The influence of lithium administration on cortical spreading depression (SD) was investigated in rats whelped by dams fed a diet containing lithium (1.5 g/kg) during the gestation or the lactation periods. Velocity of SD propagation was measured when the rats became adults and was similar to that of rats raised on a normal diet. A third group of adult rats(More)
We investigated the effects of early environmental stimulation on spreading depression in the cerebral cortex of male Wistar adult (90 day old) well-nourished (23% protein diet) and early malnourished (8% protein) rats. Environmental stimulation was performed during the suckling period or after weaning. Control rats were housed in a standard environment.(More)
Acute dehydration (D) early in life made adult rats less susceptible to cortical spreading depression (SD) than control (C) rats. Post weaning undernourished (U) rats tended to be more susceptible than controls. The association of D and U (DU group) made rats more susceptible to SD than U-rats. It is suggested that this association gives rise to a more(More)
Two compounds ("Prothemol" and "Plasmel"), based on bovine blood as source of high quality-protein, were tested as supplement for malnourished children. Prothemol is a powder containing desiccated bovine red cells, with 23.32 g% protein and 18.8 mg% iron, without any limiting amino acid. Plasmel (a syrup) contains 44.7% bovine plasma, 54.3% saccharose and(More)
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