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BACKGROUND Female athletes are at significantly greater risk of anterior cruciate ligament (ACL) injury than male athletes in the same high-risk sports. Decreased trunk (core) neuromuscular control may compromise dynamic knee stability. HYPOTHESES (1) Increased trunk displacement after sudden force release would be associated with increased knee injury(More)
Dasatinib and nilotinib are potent tyrosine kinase inhibitors (TKIs) with activity against many imatinib-resistant chronic myeloid leukemia (CML) clones with BCR-ABL kinase domain (KD) mutations, except T315I. We assessed for changes in the BCR-ABL KD mutation status in 112 patients with persistent CML who received a second-generation TKI after imatinib(More)
Stability is one of the most fundamental concepts to characterize and evaluate any system. This term is often ambiguously used in spinal biomechanics. Confusion arises when the static analyses of stability are used to study dynamic systems such as the spine. Therefore, the purpose of this paper is to establish a common ground of understanding, using(More)
This paper focused on the relationship between trunk stiffness and postural control during unstable seated balancing. We hypothesized that an increase in trunk stiffness would degrade postural control, and further hypothesized that signal dependent noise (SDN), resulting in increased muscle force variability, was responsible for this impairment. Ten(More)
BACKGROUND In sports involving pivoting and landing, female athletes suffer knee injury at a greater rate than male athletes. HYPOTHESES Proprioceptive deficits in control of the body's core may affect dynamic stability of the knee. Female, but not male, athletes who suffered a knee injury during a 3-year follow-up period would demonstrate decreased core(More)
It has been well documented that low-back pain (LBP) patients have longer muscle response latencies to perturbation than healthy controls. These muscle responses appear to be reflexive and not voluntary in nature, and as a result, might be useful for objectively classifying LBP. The goal of the study was to develop an objective and accurate method for(More)
OBJECTIVES To compare the strength of augmented versus nonaugmented fixation techniques for stabilizing vertical shear femoral neck fractures. METHODS Two surgical screw constructs were tested with and without augmentation using 40 composite femurs: (1) 7.3-mm cannulated screws placed in an inverted triangular configuration and (2) 135-degree dynamic hip(More)
BACKGROUND Impaired proprioception in the lumbar spine has often been reported in people with low back pain. However, no prospective studies exist to assert the cause and effect of this association. We hypothesized that athletes with a history of low back injury (LBI) would demonstrate poorer lumbar position sense (PS) than athletes without a history of(More)
The performance of two computerized algorithms for the detection of muscle onset and offset was compared. The standard deviation (SD) method, a commonly used algorithm, and the approximated generalized likelihood ratio (AGLR) method, a more recently developed algorithm, were evaluated at different levels of background surface EMG (sEMG) activity. For this(More)
This paper introduces control concepts that are important for ensuring stability. To clarify these concepts, a series of experiments using a simple task of stick balancing will be performed. The lessons from these experiments will be applied to the spine system and illustrated with clinical examples. Insight into the following will be gained: what(More)