N. P. Saksonov

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Parameters of binding of cortisone and estradiol to plasma membranes of rat hepatocytes were studied by the method of liquid scintillation radiometry. The presence of two systems for the binding of these hormones in the membranes was demonstrated. One system is specific (saturable) and binds hormones in physiological concentrations. The capacity and(More)
The dynamics of distribution of 125I- and 131I-bilignost in intact rats has been studied in experimental pathological condition of the liver. It has been shown that the cholecystographic radiographic contrast agent (RCA) bilignost is absorbed and accumulated mainly by the liver. This indicates that the preparation elicits a selective action with respect to(More)
Hydrocor t i sone cons iderably inc reased prote in synthes is in the m i c r o s o m a l f rac t ion (as r e f lected by incorpora t ion of g l y c i n e l C 14) in exper imen t s on ra t s . Tes tos t e rone propionate i nc reased protein b iosynthes is in this f rac t ion to a l e s s e r degree . Es t rad io l dipropionate affected prote in synthes is(More)
Daily injections of prednisolone (10 mg/kg) for a space of 7 days to albino male-rats cause an increased synthesis of nuclear and mitochondrial proteins without changing the protein synthesis of other liver fractions. Following injection of prednisolone the protein synthesis in the spleen went up and in the thymus remained unchanged. This was paralleled by(More)
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