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Journals and Conferences
Pretreatment of an affinity-purified, brain calmodulin (CaM)-dependent phosphodiesterase (EC 126.96.36.199) with p-hydroxyphenylglyoxal (pHPG), a specific arginine-modifying reagent, resulted in a time-dependent loss in CaM-stimulated hydrolysis of cyclic AMP and cyclic GMP with no change in basal, CaM-independent activity. The loss in CaM-stimulated activity… (More)