N. N. Yarmukhamedov

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Synthetic analogs of natural 3-azabicyclo[3.3.1]nonanes have drawn the attention of researchers as potential drugs [1 – 3]. This study was aimed at the synthesis of 3-(2-hydroxyethyl)-1,5-dinitro-3-azabicyclo[3.3.1]non-6-ene (II) and N-(2-hydroxyethyl)cytosine (IV) and evaluation of the antiarrhythmic activity of these compounds in the form of(More)
(1,3-Dimethyl-5-nitro-5-hexahydropyrimidinyl)propionic acid methyl ester (I) was obtained with a 83% yield using a Mannich type reaction of 4-nitrobutanoic acid methyl ester with excess formalin and methylamine. It was found that compound I possesses low toxicity and shows antiarrhythmic activity on models of arrhythmia induced by intravenous injections of(More)
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