N. N. Bogolepov

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Electron microscopy of the sensomotor cortex in 27 rats was performed at varying times (1, 3, 7 days) after arteria carotis communis occlusion. Three groups of rats (5 rats in every group) were treated by nootropil (500 mg/kg daily) in accordance with three time intervals. Control rats were undrugged. More preserved were neurons in the brain of rats treated(More)
Submicroscopic changes of neurons, synapses, glial cells and some elements of capillaries were established by studying chronic mirror foci which appeared in the rat cerebral cortex after implantation of cobalt-gelatinous rods into the contralateral hemisphere. The results were compared with normal control cortex and with changes after thermocoagulation of(More)
Studies on white mongrel rats addressed the reorganization of the synaptoarchitectonics of layer I of the cerebral cortex in diffuse-focal injuries. The experiments used models of acute arrest of the systemic circulation (clinical death) resulting from exposure to mechanical asphyxia for 6 min, clamping of the common carotid arteries for 20 min (ischemia),(More)
Syncytial interneuronal connections in the sensorimotor cortex and caudate nucleus were studied in 20 rats of 14–22 days of intrauterine development. While the development of glial processes was extremely weak, many neuron bodies and their processes were in direct contact with each other. Contacting membranes formed extended and punctate contacts(More)
Wistar rats with different levels of resistance to emotional stress (ES) were subjected to stress and brain sections stained with Nissl cresyl violet were used for quantitative analysis of the structural organization of neurons in layer V of the sensorimotor cortex. Some animals received delta sleep-inducing peptide (DSIP) 1 h before stress. Control(More)
Wistar rats behaviorally active in the open field test (resistant to emotional stress) are characterized by polymorphism of neurons in layer V of the sensorimotor cortex and the presence of hyperchromatic cells, which probably determines resistance to emotional stress in these rats. Atrophy of hyperchromatic neurons reflecting transient inhibition of cell(More)
The paper deals with electron microscopic studies of the cerebral cortex in human beings aged 70-80 years. The synapses show a decrease in the number of synaptic vesicles, their impaired distribution in the presynaptic process. There are changes in the mechanisms of interaction of synaptic vesicles and a presynaptic membrane. In the latter, the vesicles(More)