N M Hurina

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95 men aged 45-65, suffering from type 2 diabetes for 0.1-20 years (4.5 +/- 1.4) were examined. Hypoandrogenia (serum testosterone < 10,4 nmol/ml) was noted in 37% of investigated patients. Hyperuricemia (HUA), defined by serum uric acid (UA) content more than 450 pmol/L, was detected in 34% of subjects. In 74% of patients there was a high level of 24h UA(More)
Hyperuricemia (HU) is considered to be a sign of metabolic syndrome as a consequence of purine metabolism disorder. To investigate alterations in uric acid (UA) methabolism, 90 subjects (M/F 53/37, aged 58 +/- 4 yr) with type 2 diabetes mellitus (DM2) were divided into 5 groups depending on the amount of excreted UA and its content in blood plasma. HU was(More)
Hemoperfusion through the granulated hemoadsorbent SCN, fibrous carbonic adsorbent AUVM and immunoadsorbent (SCN with immobilized MBP) was applied for the treatment of experimental allergic encephalomyelitis (EAE) in guinea pigs. EAE was induced by single subcutaneous injection of 100 microg of MBP in complete Freund's adjuvant. Hemoperfusion was performed(More)
Enterosorption with highly dispersed fibrous carbon adsorbent Belosorb or enzyme-containing fibrous carbon adsorbent Panzysorb was applied for the treatment of experimental acute pancreatitis (EAP) in the rats. Panzysorb was obtained by immobilization of digestive hydrolases (proteases and amylase) on Belosorb as matrix. It was shown that oral(More)
Consumption of dietary fructose has been recently suggested to be one of the environmental factors contributing to development of obesity and accompanying abnormalities of the insulin resistance syndrome (IRS). IRS was induced in rats by adding 10% fructose to drinking water. Within 8 wk insulin resistance, carbohydrate metabolism disorder, weight gain,(More)
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