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Because stress and depression are prevalent in the elderly, the opportunity for pain to intensify stress and depression may be greater in older people than in the general population. Evidence that pain-related psychosomatic complaints are more frequent in the elderly further complicates the issue. Antidepressants that affect serotonergic systems may have(More)
4625 Background: Treatment of brain metastases (BM) remains a major concern among patients (pts) with metastatic renal cell cancer (mRCC). Previous retrospective reports suggest that TKI (especially sunitinib) can be safely used in patients with asymptomatic or previously treated BM. This prospective trial evaluates efficacy and safety in pts with non(More)
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