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Acid-sensing ion channels (ASICs) are cationic channels activated by extracellular acidosis that are expressed in both central and peripheral nervous systems. Although peripheral ASICs seem to be natural sensors of acidic pain (e.g., in inflammation, ischaemia, lesions or tumours), a direct demonstration is still lacking. We show that approximately 60% of(More)
We introduce a robust method for computing viscous and viscoelastic two-phase bubble and drop motions. Our method utilizes a coupled level-set and volume-of-fluid technique for updating and representing the air-water interface. Our method introduces a novel approach for treating the viscous coupling terms at the air-water interface; these improvements(More)
Adipose tissue is an alternative source of mesenchymal stem cells and human adipose-derived stem cells (ASCs) display an attractive and substantial therapeutic potential when transplanted in animal models. To this end, an understanding of ASC biology is necessary and the knowledge of mechanisms that maintain ASCs in an undifferentiated state with no loss of(More)
We report on attempts to construct and simulate low intensity sources of Cerenkov radiation with accurately known spectral intensity. These sources will be used to calibrate photomultipliers for the Sudbury Neutrino Observatory. We have used ^Sr as a radioactive beta source located at the center of a sphere of ultraviolet transparent acrylic. The production(More)
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