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Following publication of a report in Health Technology Assessment the NHS is running a pilot scheme screening women for human papillomavirus if they have a mildly dyskaryotic or borderline smear. 1 How reliable is testing for human papillomavirus as a marker for high grade disease in those with mildly abnormal smears? Three hundred and thirty three(More)
STUDY OBJECTIVE To assess the emotional responses of women attending a colposcopy clinic for investigation of an abnormal cervical smear, and to elicit the women's views on the screening service and colposcopy clinic. DESIGN Over 12 months all new attenders at a colposcopy clinic were invited to join the study. They were assessed psychiatrically four(More)
The factors necessary for protective immunity against HIV-1 are unknown. Important information about these factors should come from study of people at high risk of HIV infection who have not apparently become infected. Among these are the estimated 60-85% of children who may be exposed in utero or perinatally to HIV-1 but do not become infected. We observed(More)
BACKGROUND Human bocavirus (HBoV) and PARV4 are newly discovered human parvoviruses. HBoV, which was first detected in respiratory samples, has a potential role in the development of human respiratory disease. The present study compared the frequencies, epidemiological profiles, and clinical backgrounds of HBoV and PARV4 infections with those of other(More)
INTRODUCTION The last 20 years has seen a marked improvement in skin cancer awareness campaigns. We sought to establish whether this has affected the presenting Breslow thickness of malignant melanoma in the South West. METHOD This is a retrospective study looking at the first presentation of melanomas from 2003 to 2011. Data was accessed using the local(More)
To investigate whether it is appropriate to assume comparability of hepatitis virus C (HCV)-RNA results across laboratories in multi-centre studies, nine laboratories of the European Paediatric HCV Network participated in an international proficiency study of HCV-RNA assays. A panel of 12 samples of different dilutions and genotypes was sent to each(More)