N I Voskresenskaia

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Allele epsilon 4 of the apolipoprotein E (APOE) gene is associated with higher risk of Alzheimer's disease (AD) in many, though not all, ethnic groups. The APOE allele and genotype frequency distributions were studied in 207 AD patients without cerebrovascular disorders, 62 AD patients with cerebrovascular disorders (combined AD), and 206 control(More)
Visual-evoked potentials (VEP) to a flash were studied in the first-order relatives of patients with Alzheimer's disease (AD) (mean age 38.2 +/- 2.6 years) in comparison with the patients (mean age 61.9 +/- 1.4 years) and age-matched normal controls. It was found that in the relatives of AD patients the latencies of N2, P3, N3 components were delayed(More)
A relationship between neurophysiological and psychological characteristics of attention was studied in 18 patients with schizophrenia and their 34 mentally healthy relatives: parents and siblings (20 subjects) and children (14 subjects). In patients, a decrease of P300 auditory evoked potentials significantly correlated with disturbances of attention(More)
Relation between leukocyte elastase (LE) activity of peripheral blood and temporal parameters of late cognitive component of event-related potentials (ERP) was studied in 36 patients with different types of schizophrenia and 28 healthy controls. Both P300 latency and amplitude correlated with LE activity in patients, but not in controls. The results suggest(More)
On the basis of a retrospective analysis of characteristics of the initial stage of Alzheimer's disease the authors showed its variability with regard to both clinical manifestations and duration. It was found that the psychopathological structure and increase in disturbances at the initial stage of Alzheimer's disease correlated with the age at the onset(More)
AIM To study the effect of selenium on adrenocortical function in patients taking glucocorticosteroids (GCS) long. SUBJECTS AND METHODS The study included 56 patients who had been long taking oral GCS for the underlying disease. Adrenocortical function was evaluated by a short synacthen test; adrenal insufficiency (mean cortisol level 8.2 microg/dl) was(More)
The visual evoked potentials (VEP), brain DC potential (DP) mapping and emotional disorders were comparatively evaluated in patients with Alzheimer's disease (AD) and age-matched healthy individuals. In AD, the severity of emotional disorders correlated with the reduction of VEP late components P 4 N 4. In patients with frequent affect oscillations, the(More)
Twenty-one cases of familial hereditary Alzheimer's disease and 17 sporadic cases were under observation. The probands' clinical status was assessed during a number of years in accordance with the standard method (based on a unified map). The clinical parameters (dementia structure, intensity of neurologic disorders, and so forth) were correlated at the(More)