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This study examined the effects of Y-27632, a selective Rho-kinase inhibitor, on organophosphate-induced acute toxicity in rats. Rats were randomly divided into four groups as control (corn oil), dichlorvos (30 mg kg(-1) i.p.), 1 and 10 mg kg(-1) Y-27632 + dichlorvos groups. Cholinergic signs (fatigue, tremor, cyanosis, hyper-secretion, fasciculations) were(More)
Tumor induced hypoglycemia is a rare paraneoplastic phenomenon. However, hypoglycemia may also occur in solid tumors of epithelial or mesenchymal origin. Hypoglycemia caused by these types of tumours is referred to as non-islet cell tumour hypoglycemia (NICTH). Sunitinib is a drug that novel, oral, multitargeted tyrosine kinase. The biologic bases of the(More)
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