N. E. Tseomashko

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The minor base convolinine was synthesized. The activity of alkaloids from plants of the genus Convolvulus and their derivatives against HeLa and Hep cancer cell cultures and primary fibroblast culture was studied. It was found that the alkaloid convolvine and its derivatives exhibited cytotoxic activity. The alkaloids N-benzylconvolvine (4) and(More)
Two bis(tetrahydroisoquinoline) derivatives of undecane were synthesized from brassylic acid and 3,4-dimethoxy-(or methylenedioxy-)phenylethylamine. It was shown that 4a and 4b were highly cytotoxic for cancer-cell cultures and less toxic to healthy cells and exhibited noticeable antimicrobial activity against Gram-positive and Gram-negative bacteria and(More)
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