N. Duewelhenke

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Osteomyelitis, osteitis, spondylodiscitis, septic arthritis, and prosthetic joint infections still represent the worst complications of orthopedic surgery and traumatology. Successful treatment requires, besides surgical débridement, long-term systemic and high-concentration local antibiotic therapy, with possible local antibiotic concentrations of 100(More)
Ziel der Arbeit ist es, ein Modell zur Testung der Bioverträglichkeit von Materialoberflächen zu evaluieren. Für gewöhnlich binden Zellen mittels von Integrinen nicht an die eigentliche Biomaterialoberfläche, sondern an adsorbierte Proteine des Serums oder der Gewebeflüssigkeiten. Um den Einfluss von Serumproteinen bei der Zelladhäsion an die(More)
The aim of the study is to describe a model for testing biocompatibility of implant materials. Usually cells do not bind the biomaterial surface itself via integrins but adsorbed proteins of blood or interstitial fluids. To eliminate the influence of serum proteins on cell adhesion to the test materials we cultivated osteoprogenitor cells and osteoblasts(More)
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