N.D. Sonawane

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The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated epithelial Cl- channel that, when defective, causes cystic fibrosis. Screening of a collection of 100,000 diverse small molecules revealed four novel chemical classes of CFTR inhibitors with Ki < 10 microM, one of which (glycine hydrazides) had many active structural(More)
Chloride concentration ([Cl-]) was measured in defined organellar compartments using fluorescently labeled transferrin, alpha2-macroglobulin, and cholera toxin B-subunit conjugated with Cl--sensitive and -insensitive dyes. In pulse-chase experiments, [Cl-] in Tf-labeled early/recycling endosomes in J774 cells was 20 mM just after internalization, increasing(More)
The aim of this paper is to present the importance of energy conservation and management, Remote monitoring &amp; Controlling of process parameters using advanced embedded web technology which is not in practices in various Indian industry. This work is done by monitoring various industries. As demand of electricity increasing tremendously there need of(More)
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