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T LYMPHOCYTES are produced in the thymus from precursors originating in the haemopoietic tissues. On entering the thymus, they undergo a programme of proliferation, T-cell receptor (TCR) gene… (More)
Premolar root form remains an important taxonomic character in hominin alpha taxonomy. Variation in detailed aspects of root structure remains poorly characterized in extant apes. This limited… (More)
We have investigated the possibility that the costimulatory signals required for activation of mature T cells also play a role in providing differentiation signals for positive selection during… (More)
South African hominin fossils attributed to Australopithecus africanus derive from the cave sites of Makapansgat, Sterkfontein, and Taung, from deposits dated between about 2 and 3 million years ago… (More)
OBJECTIVES The premolar sub-cervical region in four non-human extant ape genera are examined to: 1) define a classification scheme for the premolar root system in order to rigorously characterize,… (More)
Abstract. The proteasome is the major cytosolic protease, composed of a 20S catalytic core that associates with either the 19S (PA700) activator or the 11S (PA28) regulator complex. The 19S complex… (More)
This paper address how additive manufacturing will revolutionize production and manufacturing industries, and ultimately determine the scope of what is possible to create. Due to its versatility,… (More)
SUMMARY Animportant factor inshaping theT-cell receptor (TcR)repertoire during thymocyte development is thesusceptibility ofdouble-positive (CD4+CD8+)thymocytes toinduction ofapoptosis (negative… (More)
T Cell Receptors.Edited by John I. Bell Michael J. Owen and Elizabeth Simpson. Oxford University Press: 1995. Pp. 483. £60, $53 (hbk); £29.50, $107 (pbk).