N. A. Skoromnyi

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Sea sickness in alert rabbits induced an increase in the local blood flow in frontal, occipital and temporal cortex as well as an increase of the total blood flow in the brain. The blood flow increases first in the temporal cortex. The changes occur at an unaltered pO2 level in the brain cortex and hypotensive response. The blood flow increase seems to be(More)
Using the hydrogen-clearance method in chronic experiments on alert rabbits, we investigated the dynamics of changes in local and total cerebral blood-flow, oxygen pressure, bioelectrical activity of the motor, auditory, and visual zones of the cerebral cortex, the heart rate during sea-sickness and the effect of the cholinolytic scopolamin upon changes in(More)
It has been established in chronic experiments on intact rabbits by the hydrogen clearance method that stimulation of the vestibular apparatus leads to an appreciable increase in the overall brain blood flow and in the regional blood flow in the frontal, occipital and temporal areas of the brain along with the development of motion sickness. Intravenous(More)
In the experiments on conscious rabbits with the electrodes implanted in the brain it was found by the methods of hydrogen clearance and polarography that piracetam (50 and 500 mg/kg) and phenibut (50 mg/kg) induced a decrease of the local blood flow in the cortex of the frontal, temporal and occipital regions and the total cerebral blood flow. The(More)
It has been shown by hydrogen clearance that diprazine (1 mg/kg) given to anesthetized cats reduces the total brain blood flow and local circulation in the cortex of the frontal lobe in the presence of a decrease in arterial pressure and blood flow in the kidneys and caudal vena cava. In intact rabbits, there is an increase in the total and local(More)
By means of hydrogen clearance on conscious rabbits with implanted platinum electrodes it was established that pyridoxine (1 and 10 mg/kg) used against the background of sea sickness decreased the dilatational reaction of the cerebral vessels occurring during the stimulation of the vestibular apparatus, reduced the blood supply to the cerebral hemispheres(More)
It was demonstrated by experiment that exposure of non-anesthetized rabbits to rocking in the head-down position at -30 degrees led to acidosis, hypoxemia and hypercapnia, changes in impedance components that were suggestive of water imbalance in the cerebral tissue, paralytic dilation of microcirculation vessels, subarachnoidal hemorrhages, hyaline(More)