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  • Byungsu Kwon, Myungwoon Lee, Alan James Waring, Mei Hong
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • 2018 (First Publication: 11 June 2018)
  • The HIV-1 glycoprotein, gp41, mediates fusion of the virus lipid envelope with the target cell membrane during virus entry into cells. Despite extensive studies of this protein, inconsistent andContinue Reading
  • Jonathan K. Williams, Daniel Tietze, Myungwoon Lee, Ji-Long Wang, Mei Hong
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • 2016 (First Publication: 23 June 2016)
  • Together with the influenza A virus, influenza B virus causes seasonal flu epidemics. The M2 protein of influenza B (BM2) forms a tetrameric proton-conducting channel that is important for the virusContinue Reading
  • Myungwoon Lee, Hongwei Yao, +4 authors Mei Hong
  • Biology, Medicine, Chemistry
  • Journal of molecular biology
  • 2018 (First Publication: 2 March 2018)
  • Enveloped viruses enter cells by using their fusion proteins to merge the virus lipid envelope and the cell membrane. While crystal structures of the water-soluble ectodomains of many viral fusionContinue Reading