Myung-Sun Kim

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Deubiquitinating enzymes regulate a number of cellular mechanisms including pre-implantation, growth and differentiation, oncogenesis, cell cycle progression, transcriptional activation, and signal transduction. In this study, we have identified a novel human deubiquitinating enzyme gene, USP22, and its mouse homologue, Usp22. They encode 525 amino acids(More)
Although results from neuropsychological and neuroimaging studies have postulated the involvement of the frontal lobe and the subcortical brain regions in the pathophysiology of obsessive-compulsive disorder (OCD), neuroimaging studies have provided little evidence that cognitive abnormalities in patients with OCD are related to dysfunctions in these areas.(More)
This study investigated the changes of the neuropsychological functions over a 4-month period of treatment in patients with obsessive-compulsive disorder (OCD). Thirty-nine OCD patients and 31 healthy controls were evaluated with neuropsychological and clinical tests. The same tests were readministered 4-months after pharmacological treatment for the OCD(More)
We describe a method for the statistical parametric mapping of low resolution electromagnetic tomography (LORETA) using high-density electroencephalography (EEG) and individual magnetic resonance images (MRI) to investigate the characteristics of the mismatch negativity (MMN) generators in schizophrenia. LORETA, using a realistic head model of the boundary(More)
In this study, we have attempted to determine the electrophysiological correlates of behavioral response inhibition in patients with obsessive-compulsive disorder (OCD). To evaluate response inhibition ability, we have used the Go/NoGo task and measured N2 and P3 event-related potential (ERP) components. Both the OCD and control groups exhibited greater and(More)
The cognitive significance of P300 abnormalities in schizophrenia and obsessive-compulsive disorder (OCD) was investigated. P300 was measured by an auditory oddball paradigm, in which a series of standard tones (1000 Hz) and target tones (1500 Hz) were presented. The subject's task was to count the number of the presented target tones. Cognitive functions(More)
PURPOSE The purpose of this study was to evaluate the results of posterior arthroscopic subtalar arthrodesis (ASTA) by use of a posterior 2-portal approach in the prone position and to describe the surgical technique. METHODS Between September 2004 and December 2006, posterior ASTA was performed in 16 patients (all men) with post-traumatic subtalar(More)
BACKGROUND The initiation of weightbearing is the focus of postoperative treatment after microfracture for osteochondral lesions of the talus. However, no comparative clinical study has been performed on early and delayed weightbearing after microfracture for osteochondral lesions of the talus. PURPOSE The aim of this prospective study was to compare the(More)
In this paper, we evaluated the long-term results of uncemented total hip arthroplasties using tapered fully porous-coated cobalt-chrome stems (Autophor 900S). The average follow-up was 206 months in 127 hips (113 patients). The articulations of the joints were ceramic-on-polyethylene in 43 hips and ceramic-on-ceramic in 84. The survival rate of the stems(More)