SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5)
- Musaab Ahmed, Myriam Fezai, Néstor L Uzcátegui, Z. Hosseinzadeh, F. Lang
- BiologyCellular Physiology and Biochemistry
- 1 January 2016
SGK3 is a positive regulator of KCNA5, which is at least partially effective by abrogating the effect of Nedd4-2, and thus did not require Na+/K+ ATPase activity.
Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
- Mohamed Jemaà, Yasmin Abassi, R. Massoumi
- BiologyScientific Reports
- 7 August 2018
It is found that the small molecule Reversine reduces the migration potential of human colon carcinoma cells in vitro and the impact of individual JNK isoforms in cancer cell metastasis is highlighted and proposed as a novel anti-cancer molecule for treatment of colon cancer patients.
SGK3 Sensitivity of Large-Conductance Ca2+-Activated K+ Channel
- Musaab Ahmed, Myriam Fezai, F. Lang
- BiologyNeurosignals
- 30 November 2016
SGK3 is a novel positive regulator of BK channels, and thus participates in the regulation of cell volume and excitability.
Methods Employed in Cytofluorometric Assessment of Eryptosis, the Suicidal Erythrocyte Death
- Mohamed Jemaà, Myriam Fezai, Rosi Bissinger, F. Lang
- Biology, MedicineCellular Physiology and Biochemistry
- 1 September 2017
The present synopsis describes the experimental procedures required for the analysis of phosphatidylserine exposure at the cell surface with annexin-V, cell volume with forward scatter, cytosolic Ca2+ activity ([Ca2+]i) with Fluo3, oxidative stress with 2′,7′-dichlorodihydrofuorescein diacetate (DCFDA), and ceramide abundance with specific antibodies.
Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397
- Mohamed Jemaà, M. Mischitelli, Myriam Fezai, Mustafa Almasry, C. Faggio, F. Lang
- BiologyCellular Physiology and Biochemistry
- 25 November 2016
Whether NSC-95397 induces eryptosis is explored and, if so, to shed some light on the mechanisms involved, an effect in part requiring entry of Ca2+ and activation of staurosporine sensitive kinase(s).
Purified Lesser weever fish venom (Trachinus vipera) induces eryptosis, apoptosis and cell cycle arrest
- Myriam Fezai, C. Slaymi, M. Ben-Attia, F. Lang, Mohamed Jemaà
- BiologyScientific Reports
- 20 December 2016
It is shown that purified Lesser weever fish venom induces eryptosis, the suicidal erythrocyte death, and apoptosis of human colon carcinoma cells and mitochondria staining cancer cells dyed after the activation of the intrinsic apoptotic pathway.
Analgesic, Anti-Inflammatory and Anticancer Activities of Extra Virgin Olive Oil
- Myriam Fezai, L. Senovilla, Mohamed Jemaà, M. Ben-Attia
- Biology, MedicineJournal of Lipids
- 23 December 2013
EVOO has a significant analgesic, anti-inflammatory, and anticancer properties, however, further detailed studies are required to determine the active component responsible for these effects and mechanism pathway.
Negative Regulation of the Creatine Transporter SLC6A8 by SPAK and OSR1
- Myriam Fezai, B. Elvira, J. Borrás, M. Ben-Attia, Zohreh Hoseinzadeh, F. Lang
- BiologyKidney & Blood Pressure Research
- 1 December 2014
Both SPAK and OSR1 are negative regulators of the creatine transporter SLC6A8, which accomplishes Na+ coupled cellular uptake of creatine in several tissues including kidney, intestine, heart, skeletal muscle and brain.
Inhibition of Suicidal Erythrocyte Death by Reversine
- Mohamed Jemaà, Myriam Fezai, F. Lang
- BiologyCellular Physiology and Biochemistry
- 27 April 2017
Reversine is a powerful inhibitor of cell membrane scrambling following energy depletion, Ca2+ loading and oxidative stress.
The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review
- Lucy M. Gorman, S. Judge, Myriam Fezai, Mohamed Jemaà, J. Harris, G. Caldwell
- Biology, ChemistryToxicon: X
- 7 February 2020
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