Myra Godfrey

Learn More
We have constructed a first-generation EST radiation hybrid comparative map of the porcine genome by assigning 1058 markers to the IMpRH7000 panel. Chromosomal localization was determined with a 2pt LOD of 4.8 for 984 markers, using the IMpRH mapping tool. Annotated ESTs represent 46.2% or 489 of the markers. Marker distribution was not stochastic and(More)
The binding of seven veterinary drugs (clenbuterol, chlorpromazine, diethylstilbestrol, 19-nortestosterone, salbutamol, salicylic acid and trenbolone) to melanin from Sepia officinalis was investigated. Basic and hydrophobic drugs were the most strongly bound. Desorption by ethanol was complete for neutral drugs but only partial for the basic drugs, which(More)
Many species of oviparous reptiles, including crocodilians, a majority of turtles, some lizards and the 2 closely related species of Sphenodon have been shown to display temperature-dependent sex determination (TSD). Whereas it has been demonstrated very early that TSD also occurs in natural conditions, the relationship between a time series of changing(More)
The Marfan syndrome (MFS) is a heritable connective tissue disorder manifested by defects in the skeletal, ocular, and cardiovascular systems. It is inherited as an autosomal dominant trait, with an incidence of nearly one per 10,000 population without gender or ethnic predilection. About 30% of MFS cases are sporadic, representing new dominant mutations.(More)
We introduce here a novel and generally applicable, solid-phase minisequencing-based approach for rapid estimation of relative levels of transcripts with high sequence homology. This study was undertaken to screen for the consequences of different fibrillin-1 mutations on the transcript levels in patients with the Marfan syndrome (MFS). This dominantly(More)
  • 1