Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Reversing the Warburg Effect as a Treatment for Glioblastoma*
- E. Poteet, G. Choudhury, +12 authors S. Yang
- Biology, Medicine
- The Journal of Biological Chemistry
- 13 February 2013
Background: Glioblastoma is the most prevalent brain tumor with the poorest prognosis. Results: Methylene blue enhances oxygen consumption, reduces lactate production, and inhibits glioblastoma cell… Expand
Pyruvate Protects the Brain Against Ischemia–Reperfusion Injury by Activating the Erythropoietin Signaling Pathway
- Myoung-Gwi Ryou, R. Liu, M. Ren, J. Sun, R. Mallet, Shao-Hua Yang
- Medicine
- Stroke
- 1 April 2012
Background and Purpose— Pyruvate is known to be cytoprotective through antioxidant and anti-inflammatory mechanisms. We tested the hypothesis that pyruvate protects the brain against… Expand
Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke
- G. R. Choudhury, Myoung-Gwi Ryou, E. Poteet, Yi Wen, S. Yang
- Biology, Medicine
- Brain Research
- 10 March 2014
Reactive astrogliosis is an essential feature of astrocytic response to all forms of central nervous system (CNS) injury and disease, which may benefit or harm surrounding neural and non-neural… Expand
Involvement of estrogen receptor β5 in the progression of glioma
- W. Li, A. Winters, E. Poteet, Myoung-Gwi Ryou, S. Yang
- Chemistry, Medicine
- Brain Research
- 29 March 2013
Emerging evidence suggests a decline of ERβ expression in various peripheral cancers. ERβ has been proposed as a cancer brake that inhibits tumor proliferation. In the current study, we have… Expand
Erythropoietin: Powerful protection of ischemic and post-ischemic brain
- A. Nguyen, Brandon H. Cherry, G. F. Scott, Myoung-Gwi Ryou, R. Mallet
- Medicine
- Experimental biology and medicine
- 4 March 2014
Ischemic brain injury inflicted by stroke and cardiac arrest ranks among the leading causes of death and long-term disability in the United States. The brain consumes large amounts of metabolic… Expand
HIV-1 Nef Is Transferred from Expressing T Cells to Hepatocytic Cells through Conduits and Enhances HCV Replication
- In-woo Park, Yan Fan, +4 authors J. He
- Biology, Medicine
- PloS one
- 9 June 2014
HIV-1 infection enhances HCV replication and as a consequence accelerates HCV-mediated hepatocellular carcinoma (HCC). However, the precise molecular mechanism by which this takes place is currently… Expand
In vitro protection by pyruvate against cadmium‐induced cytotoxicity in hippocampal HT‐22 cells
- E. Poteet, A. Winters, L. Xie, Myoung-Gwi Ryou, R. Liu, S. Yang
- Biology, Medicine
- Journal of applied toxicology : JAT
- 1 August 2014
Cadmium is a toxic metal with no biological function in higher‐order mammals. Humans are exposed to cadmium environmental contamination and the mechanism underlying the cadmium's cytotoxicity is… Expand
An In Vitro Oxygen-Glucose Deprivation Model for Studying Ischemia-Reperfusion Injury of Neuronal Cells.
- Myoung-Gwi Ryou, R. Mallet
- Medicine
- Methods in molecular biology
- 2018
Ischemia-reperfusion syndromes of the heart and brain are the leading cause of death and long-term disability worldwide. Development of effective treatments for myocardial infarction, stroke, cardiac… Expand
Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest
- G. F. Scott, A. Nguyen, +5 authors R. Mallet
- Medicine
- Experimental biology and medicine
- 31 March 2017
Cardiac arrest (CA) and cardiocerebral resuscitation (CCR)-induced ischemia–reperfusion imposes oxidative and carbonyl stress that injures the brain. The ischemic shift to anaerobic glycolysis,… Expand
Pyruvate-fortified cardioplegia suppresses oxidative stress and enhances phosphorylation potential of arrested myocardium.
- E. M. Knott, Myoung-Gwi Ryou, +6 authors A. Olivencia-Yurvati
- Chemistry, Medicine
- American journal of physiology. Heart and…
- 1 September 2005
Cardioplegic arrest for bypass surgery imposes global ischemia on the myocardium, which generates oxyradicals and depletes myocardial high-energy phosphates. The glycolytic metabolite pyruvate, but… Expand