Myles W O'Brien

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OBJECTIVE To report neuroimaging findings in patients with complex partial status epilepticus. BACKGROUND During status epilepticus, neuroimaging may be used to exclude other neurologic conditions. Therefore, it is important to identify the neuroimaging features that are associated with status epilepticus. In addition, MRI characteristics may provide(More)
BACKGROUND Diffusion-weighted (DWI) and perfusion-weighted (PWI) MRI are powerful new techniques for the assessment of acute cerebral ischemia. However, quantitative data comparing the severity of clinical neurologic deficit with the results of DWI or PWI in the earliest phases of stroke are scarce. Such information is vital if MRI is potentially to be used(More)
BACKGROUND AND PURPOSE Serial study of such MR parameters as diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC), ADC with fluid-attenuated inversion recovery (ADC(FLAIR)), and T2-weighted imaging may provide information on the pathophysiological mechanisms of acute ischemic stroke. Our goals were to establish the natural evolution of MR(More)
BACKGROUND Knowledge of the natural evolution of ischemic brain lesions may be a crucial aspect in the assessment of future stroke therapies. OBJECTIVE To establish daily changes of ischemic cerebral lesion volume using diffusion-weighted magnetic resonance imaging. DESIGN Prospective cohort study. SETTING Referral center. PATIENTS AND METHODS(More)
BACKGROUND Transient global amnesia is a well-described complication of cerebral angiography. Speculation about the pathophysiology exists but is as yet unsubstantiated. Diffusion-weighted MRI is a new imaging technique that is very sensitive in detecting acute ischemia. Its use in the evaluation of transient amnesia precipitated by cerebral angiography has(More)
OBJECTIVE To determine whether diffusion-weighted imaging (DWI) could identify potentially clinically relevant findings in patients presenting more than 6 hours after stroke onset when compared with conventional MRI. METHODS MRI with both conventional (T2 and proton density images) and echoplanar imaging (DWI and apparent diffusion coefficient maps) was(More)
Most studies of depression after stroke have included heterogeneous samples of patients. These studies have generally not qualified patients as to age, absence of neurologic, psychiatric, and substance abuse histories, and other complicating factors. Of 155 inpatient rehabilitation admissions after acute unilateral cerebrovascular accident, only 26 met the(More)
INTRODUCTION Although basilar artery stenosis (BAS) is an important cause of posterior circulation stroke, few reports detail the clinical and neuroradiological features of patients with BAS. METHODS A retrospective review of symptomatic BAS patients who were evaluated by our Stroke Center. RESULTS Twenty-eight patients were followed-up for a median of(More)
The Exercise is Medicine Canada (EIMC) initiative promotes physical activity counselling and exercise prescription within health care. The purpose of this study was to evaluate perceptions and practices around physical activity counselling and exercise prescription in health care professionals before and after EIMC training. Prior to and directly following(More)
The purpose of this study was to evaluate the accuracy of 2 newly developed physical activity questionnaires: the Canadian Society for Exercise Physiology (CSEP) Physical Activity and Sedentary Behaviour Questionnaire (PASB-Q) and a newly modified Leisure-Time Physical Activity Questionnaire (mLTPA-Q). These questionnaires were compared with objective(More)