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Many systems in sciences, engineering and nature can be modeled as networks. Examples include the internet, WWW and social networks. Finding hidden structures is important for making sense of complex networked data. In this paper we present a new network clustering method that can find clusters in an agglomerative fashion using structural similarity of(More)
Biological systems can be modeled as complex network systems with many interactions between the components. These interactions give rise to the function and behavior of that system. For example, the protein-protein interaction network is the physical basis of multiple cellular functions. One goal of emerging systems biology is to analyze very large complex(More)
Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. In current practice, dermatologists determine lesion area by manually drawing lesion borders. Therefore, automated assessment tools for dermoscopy images have become an important research field mainly because of inter- and intra-observer(More)
Computer-aided segmentation and border detection in dermoscopic images is one of the core components of diagnostic procedures and therapeutic interventions for skin cancer. Automated assessment tools for dermoscopy images have become an important research field mainly because of inter- and intra-observer variations in human interpretation. In this study, we(More)
Histopathology, one of the most important routines of all laboratory procedures used in pathology, is critical for the diagnosis of cancer. Experienced pathologists read the histological slides acquired from biopsy specimen in order to outline malignant areas. Recently, in terms of histological image analysis the improvements in imaging techniques led to(More)
Many systems in sciences, engineering and nature can be modeled as networks. Examples are internet, metabolic networks and social networks. Network clustering algorithms aimed to find hidden structures from networks are important to make sense of complex networked data. In this paper we present a new clustering method for networks. The proposed algorithm(More)
This study is a continuation of a work published by Mete, Ou, and Sirakov (2012), where a model of a 4D manifold of feature vectors was developed. The present paper introduces an improved metric in the 4D manifold first and then extends both the size of the sample space and the dimension (to 6D) of the manifold model in which the sample space lies. As a(More)
BACKGROUND AND OBJECTIVES Induction therapy with IL-2 receptor antagonist (IL2-RA) is recommended as a first line agent in living donor renal transplantation (LRT). However, use of IL2-RA remains controversial in LRT with tacrolimus (TAC)/mycophenolic acid (MPA) with or without steroids. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The Organ Procurement(More)
Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Automated assessment tools for dermoscopy images have become an important research field mainly because of inter- and intra-observer variations in human interpretation. One of the most important steps in dermoscopy image analysis is(More)
Histopathology, which is one of the most important routines of all laboratory procedures used in pathology, is decisive for the diagnosis of cancer. Experienced histopathologists review the histological slides acquired from biopsy specimen in order to outline malignant areas. Recently, improvements in imaging technologies in terms of histological image(More)