Mustafa Zeki

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Neuronal persistent activity has been primarily assessed in terms of electrical mechanisms, without attention to the complex array of molecular events that also control cell excitability. We developed a multiscale neocortical model proceeding from the molecular to the network level to assess the contributions of calcium (Ca(2+)) regulation of(More)
Abstract—A novel circuit for generating a signal embedded with features about data from three sensors is presented. This suggested circuit is making use of a resistance-to-time converter employing a bridge amplifier, an integrator and a comparator. The second resistive sensor (Rz) is transformed into duty cycle. Another bridge with varying resistor, (Ry) in(More)
Working memory corresponds to our ability to store and manipulate information for a short time in order to carry out complex cognitive tasks. The brain region most closely associated with working memory is the prefrontal cortex; neurons within the PFC show sustained elevated activity that persists after the removal of a stimulus. It is believed that this(More)
Persistent irregular activity is defined as elevated irregular neural discharges in the brain in such a way that while the average network activity displays high frequency oscillations, the participating neurons display irregular and low frequency oscillations. This type of activity is observed in many brain regions like prefrontal cortex that plays a role(More)
This paper is concerned with the biological neuron model of Morris–Lecar system of equations (Morris and Lecar, 1981) [17]. We prove the existence and uniqueness of strong solutions. In addition, we prove the continuous dependence of solutions to the leak conductance parameter. © 2015 Elsevier Inc. All rights reserved.
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