Mustafa Turhan Coban

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In the brain, Notch signaling maintains normal neural stem cells, but also brain cancer stem cells, indicating an oncogenic role. Here, we identify an unexpected tumor suppressor function for Notch in forebrain tumor subtypes. Genetic inactivation of RBP-Jκ, a key Notch mediator, or Notch1 and Notch2 receptors accelerates PDGF-driven glioma growth in mice.(More)
When simulating refrigeration systems or equipment, knowledge of refrigerant thermodynamic properties is required. While some of the refrigerants are made of pure fluids, some of these refrigerants are made by mixing of two or more pure refrigerants with the predetermined percentages. Properties of refrigerants are a major part of international trade,(More)
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