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Ca2+ Entry, Oxidative Stress, Ceramide and Suicidal Erythrocyte Death Following Diosgenin Treatment.

• Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The bioactive steroid sapogenin diosgenin is considered for a wide variety of applications including treatment of malignancy. The substance counteracts tumor growth in part by… (More)

Triggering of Suicidal Erythrocyte Death by Fascaplysin.

• Morena Mischitelli, Mohamed Mekki Ben Jemaa, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The bis-indole alkaloid Fascaplysin is effective against malignancy, an effect at least partially due to stimulation of tumor cell apoptosis. Similar to apoptosis of nucleated cells,… (More)

Stimulation of Suicidal Erythrocyte Death by Phosphatase Inhibitor Calyculin A.

• Mustafa Almasry, Mohamed Jemaà, Morena Mischitelli, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The serine/threonine protein phosphatase 1 and 2a inhibitor Calyculin A may trigger suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes… (More)

Triggering of Erythrocyte Cell Membrane Scrambling by Emodin.

• Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The natural anthraquinone derivative emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a component of several Chinese medicinal herbal preparations utilized for more than 2000 years.… (More)

Camalexin-Induced Cell Membrane Scrambling and Cell Shrinkage in Human Erythrocytes.

• Mustafa Almasry, Mohamed Mekki Ben Jemaa, Morena Mischitelli, Florian Lang, Caterina Faggio
• Cellular physiology and biochemistry…
• 2017

BACKGROUND/AIMS The thaliana phytoalexin Camalexin has been proposed for the treatment of malignancy. Camalexin counteracts tumor growth in part by stimulation of suicidal death or apoptosis of tumor… (More)

Stimulation of Suicidal Erythrocyte Death by Rottlerin.

• Morena Mischitelli, Mohamed Mekki Ben Jemaa, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The phytochemical polyphenol rottlerin is a potent activator of diverse Ca2+ -sensitive K+ channels. Those channels play a decisive role in the execution of eryptosis, the suicidal… (More)

Stimulation of Erythrocyte Cell Membrane Scrambling by Quinine.

• Morena Mischitelli, Mohamed Jemaà, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The analkaloid drug quinine is utilized mainly for the chemoprophylaxis of malaria. The multiple side effects of quinine include hemolytic anemia and hemolytic uremic syndrome,… (More)

Stimulation of Erythrocyte Cell Membrane Scrambling by Adarotene.

• Morena Mischitelli, Mohamed Jemaàa, MyriamFezai Fezai, Mustafa Almasry, Florian Lang, Caterina Faggio
• Cellular physiology and biochemistry…
• 2017

BACKGROUND/AIMS The atypical retinoid E23-(40-hydroxyl-30-adamantylbiphenyl-4-yl) acrylic acid (ST1926, adarotene) is used in the treatment of malignancy. The effect of ST1926 is at least in part due… (More)

Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397.

• Mohamed Mekki Ben Jemaa, Morena Mischitelli, Myriam Fezai, Mustafa Almasry, Caterina Faggio, Florian Lang
• Cellular physiology and biochemistry…
• 2016

BACKGROUND/AIMS The CDC25B inhibitor NSC-95397 triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy. The substance is effective in part by modification of gene… (More)

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