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Journals and Conferences
The antiproliferative and antimicrobial effects of thirteen compounds isolated from Inula viscosa (L.) were tested in this study. The antiproliferative activity was tested against three cell lines using the MTT assay. The microdilution method was used to study the antimicrobial activity against two Gram positive bacteria, two Gram negative bacteria and one… (More)
Investigation of Capparis spinosa of Jordanian origin lead to isolation of two new compounds beta-sitosterylglucoside-6'-octadecanoate (1) and 3-methyl-2-butenyl-beta-glucoside (2). Linked Scan MS measurements were used to propose a mass fragmentation pattern for the alkaloid Cadabicine isolated here for the second time from nature.
The effects of the flavone 3,3'-di-O-methylquercetin (DOMQ) have been examined and compared with those of quercetin, on guinea-pig isolated ileum, trachea, and main pulmonary artery (MPA). Except for transient contractions induced by low concentrations (10(-8)-3 x 10(-6) M), DOMQ and quercetin (up to 3 x 10(-4) M) caused reduction of the tone and the phasic… (More)
Two new withanolides named mandragorolide A (1) and mandragorolide B (2) were isolated from the MeOH extract of the whole plant of Mandragora officinarum of Jordanian origin, along with five known withanolides namely larnaxolide A (3), withanolide B (4), datura lactone 2 (5), withanicandrin (6) and salpichrolide C (7). Compound 3 has been reported only once… (More)
Seventeen compounds, including a new lanostane triterpenoid, 24(Z)-1β-3β-dihydroxyeupha-7,24-dien-26-oic acid, have been isolated from the methanolic extracts of two samples of Jordanian propolis collected from two different places with different dominant flora. The structures of the isolated compounds were elucidated by spectral methods including IR, UV,… (More)
Dracaena cinnabari, known as the dragon’s blood tree, has been used for long time in the Yamani and Arabian folk medicine for many claimed ailments. Chemical analysis of the resin of D. cinnabari resulted in the isolation of the five flavonoiud from the chloroform extract: 4,4’-dihydroxy-2’-methoxychalcone, 4,4’-dihydroxy-2methoxydihydrochalcone,… (More)
Investigation of Inula viscosa of Jordanian origin afforded the new sesquiterpene 1beta-hydroxyilicic acid in addition to the known 2beta-hydroxyilicic acid.
1. The effects of (-)oblongine chloride, a quaternary alkaloid from Leontice leontopetalum, on guinea-pig isolated ileal longitudinal segments, main pulmonary artery rings, spontaneously-beating atrium and isolated perfused heart were studied. 2. Oblongine chloride (3 x 10(-5)-10(-3) M) caused concentration-dependent relaxation of ileum, an effect which was… (More)
From Colchicum ritchii R.Br (Liliaceae) of Jor danian origin, the new colchicine-type alkaloid (-)-O -m ethylspeciosine (1), the known alkaloid (-)-speciosine (2) and two new homoaporphine/V-oxides are isolated and characterized: (+)-kreysigine-/V-oxide (5) and (+)-szovitsamine-./V-oxide (6). Additinally, two photoisomers of the cholchicine alkaloids are… (More)