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- Natalie Jane Beveridge, Erin J Gardiner, Adam P. Carroll, Paul A. Tooney, Murray J. Cairns
- Molecular Psychiatry
- 2010
MicroRNA expression profiling and quantitative reverse transcription-PCR analysis of the superior temporal gyrus and the dorsolateral prefrontal cortex revealed a significant schizophrenia-associated… (More)
- Natalie Jane Beveridge, Paul A. Tooney, +6 authors Murray J. Cairns
- Human molecular genetics
- 2008
Analysis of global microRNA (miRNA) expression in postmortem cortical grey matter from the superior temporal gyrus, revealed significant up-regulation of miR-181b expression in schizophrenia. This… (More)
- Stuart G Fillman, Nicole Cloonan, +5 authors Cynthia Shannon Weickert
- Molecular Psychiatry
- 2013
Upregulation of the immune response may be involved in the pathogenesis of schizophrenia with changes occurring in both peripheral blood and brain tissue. To date, microarray technology has provided… (More)
- Guy Barry, James A. Briggs, +14 authors John S. Mattick
- Molecular Psychiatry
- 2014
Schizophrenia (SZ) is a complex disease characterized by impaired neuronal functioning. Although defective alternative splicing has been linked to SZ, the molecular mechanisms responsible are… (More)
- Ross J. Tynan, Judith Weidenhofer, Madeleine Hinwood, Murray J. Cairns, Frederick Rohan Walker
- Brain, Behavior, and Immunity
- 2012
Selective serotonin and serotonin norepinephrine reuptake inhibitors (SSRI; SNRI) are the first choice pharmacological treatment options for major depression. It has long been assumed that the… (More)
- Verneri Anttila, Brendan K. Bulik-Sullivan, +497 authors Benedicto Crespo-Facorro
- Science
- 2018
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain… (More)
- Danielle M. Santarelli, Natalie Jane Beveridge, Paul A. Tooney, Murray J. Cairns
- Biological Psychiatry
- 2011
BACKGROUND
MicroRNA (miRNA) are capable of regulating multitudes of target genes and are essential factors in mediating healthy neurodevelopment. We hypothesize that abnormal miRNA levels contribute… (More)
- Erin J Gardiner, Natalie Jane Beveridge, +4 authors Murray J. Cairns
- Molecular Psychiatry
- 2012
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level and are important for coordinating nervous system development and neuronal function in the mature brain. We have recently… (More)
- Graham S Plastow, Domingo Carrión, +29 authors Sarah C. Blott
- Meat science
- 2005
Functional genomics, including analysis of the transcriptome and proteome, provides new opportunities for understanding the molecular processes in muscle and how these influence its conversion to… (More)
- Murray J. Cairns, T. M. Hopkins, Craig Witherington, Li Wang, Lun-Quan Sun
- Nature Biotechnology
- 1999
A small catalytic DNA, known as the 10–23 DNA enzyme or deoxyribozyme, has been shown to efficiently hydrolyze RNA at purine-pyrimidine (R-Y) junctions in vitro. Although these potentially cleavable… (More)