Murat İrkeç

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Dry eye disease (DED) is a distressing ocular condition. Due to its multifactorial nature, clinical and biological signs of DED can be inconsistent and sometimes discordant with symptomatology. Consequently, no gold-standard model for determining DED severity exists. This can impact treatment decisions and complicate evaluation of disease progression,(More)
PURPOSE To compare the retinal nerve fiber layer [RNFL] thickness of the amblyopic eye with that of the normal eye in patients with anisometropic and strabismic amblyopia. METHODS Scanning laser polarimetry was performed with the GDx Nerve Fiber Analyzer (NFA), a scanning laser ophthalmoscope that measures the thickness of the peripapillary RNFL(More)
PURPOSE To investigate the association of lysyl oxidase like 1 (LOXL1) variants with exfoliation syndrome (XFS), exfoliation glaucoma (XFG), and primary open angle glaucoma (POAG) in a Turkish population. METHODS Two LOXL1 single nucleotide polymorphisms (SNPs), rs1048661 (R141L) and rs3825942 (G153D), were analyzed in 300 Turkish patients (100 patients(More)
PURPOSE To determine the optic nerve head topographic parameters with the least variability in repeat measurements. METHODS We randomly selected and evaluated 1 eye each of 20 healthy subjects, a total of 20 eyes. We used the confocal scanning laser ophthalmoscope (CSLO) for optic nerve head analysis. The disc area and a total of 13 parameters were(More)
This report aims to describe the facilitating role of in vivo confocal microscopy in differentiating inflammatory cells from a metastatic process in a patient with uveal melanoma and multiple systemic metastases who developed anterior uveitis while under ipilimumab treatment. A 43-year-old woman developed systemic metastases 11 months after treatment of(More)
PURPOSE To determine the effect of scan repetition during a single visit for improved reproducibility of optic nerve head topographic measurements. METHODS One randomly selected eye of 20 healthy subjects with no systemic or ocular disease was evaluated. Half of the subjects were under 30 years of age and the other half were older than 60 years. Five(More)
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