Muhittin Emre Ozdemir

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BACKGROUND A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental tests. Currently, there are a large number of computational methods that predict the activity of drugs on proteins. In this study, we approach the activity prediction problem as a(More)
Structure-based drug design approach is used to design and analyze cytochrome P450 inhibitors for the treatment of prostate cancer. The structural efficiency of inhibitors is measured by the ability of the designed inhibitors to form interactions with atoms in the active site of cytochrome P450 that includes a heme group. Docking studies are conducted to(More)
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