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Requirements for model server enabled collaborating on building information models. copies of full i tems can be reproduced, displayed or performed, and given to third parties in any format or medium for personal research or study, educational, or not-for-profit purposes without prior permission or charge, provided the authors, ti t le and full… (More)
The present study describes a convenient method for the synthesis of new lipoxygenase inhibitors, 4-(toluene-4-sulfonylamino)-benzoic acids from p-amino benzoic acid. Reaction of p-amino benzoic acid with p-toluenesulfonyl chloride provided thirteen N- and O-alkylation products 4a-4m in moderate to good yields. Lipoxygenase inhibition of newly formed… (More)
In the crystal structure of the title compound, K(+)·C(6)H(4)IO(3)S(-)·H(2)O, the potasium cation is 2.693 (3)-2.933 (3) Å from the sulfonate and water O atoms (including symmetry-related atoms) and forms a two-dimensional sheet-like structure in the bc plane, with the iodo-benzene rings protruding above and below. The water mol-ecule of crystallization is… (More)
In the mol-ecule of the title compound, C(13)H(9)ClINO(4)S, the coordination around the S atom is distorted tetra-hedral. The aromatic rings are oriented at a dihedral angle of 74.46 (9)°. Intra-molecular C-H⋯O hydrogen bonds result in the formation of two five- and one six-membered rings, which adopt planar, envelope and twisted conformations,… (More)
The crystal structure of the title compound, C(14)H(21)NO(2)S, is a polymorph of the structure reported by Khan et al. [Acta Cryst. (2009), E65, o2867] which is also monoclinic (space group P2(1)/c). The unit cell in the title structure is approximately half the volume of the previously reported polymorph and the asymmetric unit of the title compound… (More)
In the title compound, C(15)H(19)Br(3)N(2)O(4)S, the thia-zine ring adopts a distorted half-chair conformation. The enolic H atom is involved in an intra-molecular O-H⋯O hydrogen bond, forming a six-membered ring. In the crystal, the mol-ecules are linked into a three-dimensional network through inter-molecular N-H⋯O, N-H⋯Br and O-H⋯Br hydrogen bonds.
The title compound, C(13)H(10)BrNO(4)S, belongs to the sulfonamide class of organic compounds. The two aromatic rings are inclined at 34.30 (15)° to one another, and the carboxyl substituent lies in the plane of the benzene ring to which it is bound (maximum deviation = 0.004 Å). In the crystal structure, charactersitic carboxylic acid dimers are formed… (More)
The title compound, C(10)H(12)BrNO(4)S, is an inter-mediate in the synthesis of benzothia-zine. The planar methyl ester group (maximum deviation is 0.0065 Å) is oriented at a dihedral angle of 39.09 (13)° with respect to the aromatic ring. In the crystal structure, weak inter-molecular C-H⋯O inter-actions link the mol-ecules into centrosymmetric dimers,… (More)
In the title compound, C(10)H(9)NO(3)S, the benzisothia-zole group is almost planar (with a maximum deviation of 1.61 Å). The crystal structure is stabilized by weak inter-molecular C-H⋯O hydrogen bonds, forming a chain of mol-ecules along b.
In the title compound, C(13)H(9)ClINO(4)S, the dihedral angle between the aromatic rings is 81.04 (17)°. The disposition of the I and Cl atoms attached to the two rings is anti. In the crystal, mol-ecules are connected via O-H⋯O and N-H⋯O hydrogen bonds.