Muhammad Safdar

Learn More
A microfluidic bioreactor with an easy to fabricate nano-plasmonic surface is demonstrated for studies of biofilms and their precursor materials via Surface Enhanced Raman Spectroscopy (SERS). The system uses a novel design to induce sheath flow confinement of a sodium citrate biofilm precursor stream against the SERS imaging surface to measure spatial(More)
Caspases are important initiators and most well-known finishers of apoptosis. By changing the death propagation homeostatic equilibrium, their different expression patterns might trigger the progression of hazardous diseases like cancer. miR-221 is an oncogenic miRNA. It is known to have both anti-angiogenic and angiogenic effect. The aim of this work was(More)
We build on the concept of hot intrusion embossing to develop a one-step fabrication method for thermoplastic microfluidic channels containing integrated three-dimensional features. This was accomplished with simple, rapid-to-fabricate imprint templates containing microcavities that locally control the intrusion of heated thermoplastic based on their(More)
As we move slowly to a paradigm where a large number of machines will interact with each other without the need for human intervention, we begin to realize that we need a standard way to enable communication between these machines. Additionally, since a lot of good work has already been done in the past to setup the Internet and the IP networks, it makes(More)
Continuing our previous research on color image compression, we move towards spectral image compression. This enormous amount of data needs more space to store and more time to transmit. To manage this sheer amount of data, researchers have investigated different techniques so that image quality can be conserved and compressibility can be improved. The(More)
We present a microfluidic device capable of patterning linear biofilm formations using a flow templating approach. We describe the design considerations and fabrication methodology of a two level flow-templating micro-bioreactor (FT-μBR), which generates a biofilm growth stream surrounded on 3 sides by a growth inhibiting confinement stream. Through a(More)
Diabetes mellitus is a metabolic disorder that is characterized by high blood glucose level, and body cannot produce enough insulin, or does not respond to the produced insulin. In spite of the diabetes education campaigns and programmes, a large number of people in the United Kingdom are living with diabetes. The main objective of the study is to evaluate(More)
This paper examines the theoretical approaches of educated people about the role of information technology in the development of education sector, with particular context of Pakistan. Quantitative (measured scale) variables and qualitative thematic variables generated from open-ended responses were analyzed by applying statistical measures, i.e. SPSS, to(More)
Linearizability criteria for systems of two cubically semi-linear second order ordinary differential equations (ODEs) were obtained by geometric means using real symmetry analysis (RSA). Separately, complex symmetry analysis (CSA) was developed to provide means to discuss systems of two ODEs. It was shown that CSA provides a class of linearizable systems of(More)
Cardiovascular disease (CVD) and chronic kidney disease (CKD) are common comorbid conditions. Life style, particularly diet is a critical component of treatment for these conditions. Register dietitians play a key role in bridging the gap between the science of nutrition and the empowerment of individuals to alter their lifestyles in a healthy manner. A(More)