Muhammad Babar

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Four different goat breeds (Pak-Angora, Dera Din Panah, Naachi and Teddy) of Pakistan were selected to investigate polymorphism in the prion protein gene (PrP gene) responsible for scrapie disease resistance in goats. Initially, genotyping of 187 animals of these four breeds by restriction fragment length polymorphism (RFLP) was done to see the genotype for(More)
α- and β-Galactosidases find application in food processing, health and nutrition. Aspergillus niger is one of the potent producer of these enzymes and was genotypically improved using gamma-ray induced mutagenesis. The mutant-derivative produced two-fold higher α- and β-galactosidases. For testing genetic variability and its relationship with phenotypic(More)
An extensive study on spontaneous and 5-Fluorodeoxyuridine induced fragile sites identified Xq31 in cattle (Bos taurus) and (Xq24, Xq26) in sheep (Ovis aries) in addition to several autosomal fragile sites (under publication). A ZOO-FISH study using three cloned human fragile-X probes with CCG/CGGn trinucleotide repeat sequence was carried out to determine(More)
In tropical and subtropical regions of the world, parasitic diseases are major obstacle in the health and ultimately overall performance of animals. Cattle express heritable, contrasting phenotypes when exposed to ticks depicting genetic nature of trait. IFN-γ is one of the most reported genes critical for innate and adaptive immunity against viral and(More)
This study was conducted on four sheep breeds, Karakul, Kajli, Thalli and Kachhi for their natural resistance against Haemonchus contortus. After deworming, 13 animals of each breed were ingested with doses of 5000 L3 of Haemonchus contortus and then evaluation of each was made on the basis of fecal egg count (FEC), body weight, FAMACHA score and packed(More)
Scrapie is a fatal neurodegenerative disease of sheep and goats, which is strongly believed to be caused by the accumulation of improperly folded forms of host-encoded cellular prion protein (PrPc) in the central nervous system (CNS). The different genotypes of prion protein gene have been shown to make animals variably susceptible to this disease. We(More)
Prion protein (PrP) gene of 308 sheep was genotyped to investigate polymorphisms at scrapie-associated codons 136, 154 and 171 to assess the resistance of nine different Pakistani sheep breeds to natural/typical scrapie. As a result six genotypes were established on the basis of polymorphic codons 154 and 171. The most scrapie-susceptible codon 136 (A/V)(More)
This study was carried out as a prerequisite to evaluate the therapeutic potential of Camellia varieties. The crude extracts of six different plants of green tea Camellia assamica and Camellia sinensis were tested against three Gram-positive and four Gram-negative bacteria using agar disk diffusion method at 50 mg/ml concentration.(More)
Boron toxicity is one of the most important environmental stresses prevailing globally, which limits grain production. In wheat, tolerance to boron toxicity has been manipulated around the Bo1 locus on 7BL chromosome. However, there is a need to identify new diversity in other Triticeae to broaden the germplasm base for genetic improvement and greater(More)
The Kail sheep breed of Azad Jammu and Kashmir (AJ&K) was analyzed by using 11 microsatellite markers in order to estimate genetic diversity of this famous breed. This study aimed to provide information on the genetic structure of the Kail breed. In total 47 samples of Kail sheep were genotyped. We obtained 58 alleles, while average number of alleles was(More)