Muhamed Kheir Taha

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To compensate for the lack of laboratories in remote areas, the national reference laboratory for meningitis in Niger used polymerase chain reaction (PCR) to enhance the surveillance of meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. PCR effectively documented the wide geographic spread of N. meningitidis(More)
The lpxA gene is known to be involved in the biosynthesis of lipid A in Gram-negative bacteria and thought to be an essential gene. However, viable meningococcal lpxA mutants devoid of detectable endotoxin (lipooligosaccharide) have been reported. We characterised such mutants in strains of Neisseria meningitidis belonging to serogroups B and C using(More)
The Neisseria gonorrhoeae pilE gene codes for a type IV pilin, the major subunit of pili which constitute an essential virulence factor during gonococcal infection. Expression of pilE seems to be highly regulated, which may allow piliation to adapt to growth conditions. From an N. gonorrhoeae genomic library, we selected plasmid pNG200 encoding a protein(More)
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