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Assessing the contribution of opioid- and dopamine-related genetic polymorphisms to the abuse liability of oxycodone
- J. Jones, Mudassir Mumtaz, J. Manubay, S. Mogali, S. Comer
- Pharmacology Biochemistry and Behavior
- 4 September 2019
BACKGROUND Attempts to identify opioid users at increased risk of escalating to opioid use disorder have had limited success. Data from a variety of sources suggest that genetic variation may mediate… Expand
Abuse liability of intravenous buprenorphine vs. buprenorphine/naloxone: Importance of absolute naloxone amount.
BACKGROUND This study sought to determine the relative importance of a range of Bup/Nx doses compared to Bup alone in producing subjective and reinforcing effects. METHODS Heroin-using volunteers… Expand
Chronic pain and opioid abuse: Factors associated with health‐related quality of life
- J. Jones, Jonathan S Vogelman, Rachel R Luba, Mudassir Mumtaz, S. Comer
- The American journal on addictions
- 1 December 2017
BACKGROUND AND OBJECTIVES While research on the separate relationships between health-related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work has… Expand