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Assessing the contribution of opioid- and dopamine-related genetic polymorphisms to the abuse liability of oxycodone
BACKGROUND Attempts to identify opioid users at increased risk of escalating to opioid use disorder have had limited success. Data from a variety of sources suggest that genetic variation may mediateExpand
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Abuse liability of intravenous buprenorphine vs. buprenorphine/naloxone: Importance of absolute naloxone amount.
BACKGROUND This study sought to determine the relative importance of a range of Bup/Nx doses compared to Bup alone in producing subjective and reinforcing effects. METHODS Heroin-using volunteersExpand
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Chronic pain and opioid abuse: Factors associated with health‐related quality of life
BACKGROUND AND OBJECTIVES While research on the separate relationships between health-related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work hasExpand
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