Mostefa Fodil

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Colorectal cancer (CRC) is a complex and multifactorial disease, in which genetic and environmental factors both seem to play a part. Many epidemiological studies have explored the association between genetic polymorphisms of X-ray repair cross-complementing group 3 (XRCC3) (Thr241Met) and Xeroderma pigmentosum group D (XPD) lysine to glutamine at codon 751(More)
The tumor suppressor gene TP53 and its regulator MDM2 are both key players involved in multiple pathways including apoptosis, cellular transcriptional control and cell cycle regulation. Common germline polymorphisms in these genes may affect colorectal cancer (CRC) susceptibility. An arginine-to-proline substitution at codon 72 in the TP53 gene is reported(More)
The aim of this study was to detect the genetic alterations in the Factor 8 gene in 26 patients from Western Algeria. We detected the presence of "intron 22 inversion" with long-range polymerase chain reaction (PCR). Negative patients for this inversion were analyzed for "intron 1 inversion" using multiplex PCR. Patients who were negative for both(More)
Faouzia Zemani-Fodil1#, Meriem Abdi1#*, Mostefa Fodil1, Meriem Samia Aberkane1, Naima Mesli2, Mohamed Belazaar3, Malika Mehalhal4, Yasmina Rahal5, Hadj Touhami5, Nadhira Saidi-Mehtar1, Abdallah Boudjema1 1Laboratoire de Génétique moléculaire et Cellulaire, Université des Sciences et de la Technologie d’Oran -Mohamed Boudiaf(USTOMB), Oran, Algeria 2Service(More)
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