Morteza Sattari

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Seeds of the cumin plant (Cuminum cyminum L.) have been used since many years in Iranian traditional medicine. We assessed the effect of cumin seed essential oil on the biofilm-forming ability of Klebsiella pneumoniae strains and on the integrity of a native resistance plasmid DNA from K. pneumoniae isolates, treated with essential oil. Antibacterial(More)
Antimicrobial properties of plants essential oils (EOs) have been investigated through several observations and clinical studies which purpose them as potential tools to overcome the microbial drug resistance problem. The aim of this research is to study the antibacterial effect of two traditional plants essential oils, Thymus vulgaris and Eucalyptus(More)
Shigatoxigenic Escherichia coli is an important cause of dysentery in domestic animals. In this study, we compared polymerase chain reaction (PCR) and serologic (through verotoxigenic escherichia coli-rapid plate latex agglutination (VTEC-RPLA) kit) methods to detect shigatoxigenic E. coli isolated from 400 fecal samples collected from cattle and calves.(More)
The aim of this study was to investigate the incidence of and resistance gene content of class 1 integrons among enteropathogenic Escherichia coli (EPEC) and non-EPEC and to investigate intraspecies genetic diversity of EPEC strains isolated from children with diarrhea in Iran. Twenty-eight EPEC and 16 non-EPEC strains isolated from children with diarrhea(More)
Cuminum cyminum L., commonly known as cumin, is a plant with a considerable reputation. The aim of this work was to study the activity of cumin seed essential oil and alcoholic extract against Klebsiella pneumoniae ATCC 13883 and clinical K. pneumoniae isolates by evaluating the effect of subminimum inhibitory concentrations (sub-MICs) on cell morphology,(More)
The bacterial superantigen staphylococcal enterotoxin B (SEB) is a potent inducer of cytotoxic T-cell activity and cytokine production in vivo. We investigated the possibility of the therapeutic application of SEB in patients with fibrosarcoma. The anti-tumor effect of SEB in mice with inoculated fibrosarcoma (WEHI-164) was examined by intravenous (IV) and(More)
Pseudomonas aeruginosa as an opportunistic pathogen causes lethal infections in immunocompromised individuals. This bacterium possesses a polar flagellum made up of flagellin subunits. Flagella have important roles in motility, chemotaxis, and establishment of P. aeruginosa in acute phase of infections. Isolation, cloning, and expression of flagellin were(More)
Aminoglycosides are potent bactericidal agents that play an important role in antistapylococcal therapy. In this study, we used a multiplex polymerase chain reaction assay to investigate the prevalence of aac(6')-Ie/aph(2''), ant(4')-Ia, and aph(3')-IIIa, the genes encoding the most clinically prevalent aminoglycoside-modifying enzymes, and simultaneous(More)
BACKGROUND AND THE PURPOSE OF THE STUDY Morphine-6-glucuronide (M6G) is a potent metabolite of morphine which has high penetration into the brain despite its high polarity, which could be the result of an active transport system involved in M6G transport through blood brain barrier. Examples of such transporters are p-glycoprotein (PGP),(More)
Cholera is an acute infection of the intestine caused by theVibrio cholerae bacterium. This bacterium, a member of Vibrionaceae family, is a facultatively anaerobic, Gram-negative, non-spore-forming curved rod, about 1.4–2.6 µm long, and capable of both respiratory and fermentative metabolism. Cholera, characterized by numerous voluminous watery stools, is(More)