Morten Braendengen

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PURPOSE Preoperative chemoradiotherapy is considered standard treatment for locally advanced rectal cancer, although the scientific evidence for the chemotherapy addition is limited. This trial investigated whether chemotherapy as part of a multidisciplinary treatment approach would improve downstaging, survival, and relapse rate. PATIENTS AND METHODS The(More)
OBJECTIVE To study the complication rate, local recurrence rate, and survival after total pelvic exenteration for primary advanced and recurrent rectal cancer. DESIGN Prospective study. SETTING Tertiary referral university hospital, Norway. SUBJECTS 25 patients who were operated on for primary advanced and 22 for recurrent rectal cancer since 1991; 42(More)
AIM Three papers including five patients have described en bloc radical prostatectomy for locally advanced rectal cancer. METHODS Six patients (median age 63 years) underwent en bloc radical prostatectomy for locally advanced (3) or recurrent (3) rectal cancer involving the prostate. Quality of life questionnaires were answered postoperatively and the(More)
INTRODUCTION Patients with skeletal metastases represent a large cohort in clinical oncology, and the single most frequent indication for palliative radiotherapy. Patients with cancer of the breast, lung, prostate and those with myelomatosis, constitute approximately 80% of this group. MATERIAL AND METHODS This paper summarizes data from relevant(More)
PURPOSE This Nordic multicenter phase II study evaluated the efficacy and safety of oxaliplatin combined with the Nordic bolus schedule of fluorouracil (FU) and folinic acid (FA) as first-line treatment in metastatic colorectal cancer. PATIENTS AND METHODS Eighty-five patients were treated with oxaliplatin 85 mg/m(2) as a 2-hour infusion on day 1,(More)
OBJECTIVE To evaluate the clinical significance of bone scans taken routinely before total cystectomy in patients with bladder cancer of clinical stage > or = T2. PATIENTS AND METHODS Of 227 consecutive patients with stage > or = T2 bladder cancer diagnosed between 1980 and 1990 but with no clinical suspicion of bone metastases, 91 had a pre-cystectomy(More)
BACKGROUND There are 3 450 new cases of colorectal cancer in Norway annually. In half of the patients, metastatic disease will evolve with time. Palliative chemo- or radiotherapy can prolong disease- and symptom control when cure is not feasible. MATERIAL AND METHODS This paper is based on publications retrieved from a PubMed search, the authors'(More)
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