Morgane Stichelbout

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SALL4 has important functions in embryonic stem cells. The aim of this study was to investigate SALL4 expression in gestational trophoblastic neoplasia. We hypothesized that it could help to distinguish choriocarcinoma, the presumed most primitive form of gestational trophoblastic neoplasia, from placental site trophoblastic tumor and epithelioid(More)
PURPOSE Blepharocheilodontic (BCD) syndrome is a rare autosomal dominant condition characterized by eyelid malformations, cleft lip/palate, and ectodermal dysplasia. The molecular basis of BCD syndrome remains unknown. METHODS We recruited 11 patients from 8 families and performed exome sequencing for 5 families with de novo BCD syndrome cases and(More)
OBJECTIVE The objectives of the study are to describe the obstetric outcomes associated with massive perivillous fibrin deposition (MFD) compared with a control series and to determine if outcome differs according to the extent of fibrin deposition. METHOD Retrospective case-control study based on placentas analyzed over a consecutive 12-year period. MFD(More)
Une femme caucasienne, âgée de 77 ans, était adressée en ophalmologie pour uvéite bilatérale granulomateuse. Elle avait pour ntécédents un nodule bénin du sein gauche, une hypertension rtérielle et ne consommait ni alcool ni tabac. Dans les mois préédant son hospitalisation, elle rapportait une discrète altération e l’état général sans symptôme respiratoire(More)
Twin pregnancies combining complete hydatidiform mole and coexistent fetus are a rare situation (incidence in 1/20,000 in 1/100,000 pregnancies) and a challenge for diagnosis. Their complications can be important - bleeding, preeclampsia, miscarriage - and their management remains complex and controversial. In case of continuing the pregnancy, nearly 40% of(More)
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