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INTRODUCTION In this study, we used the finite element method to examine the optimum conditions for parallel translation of the anterior teeth under a retraction force. METHODS Finite element models of the 6 maxillary anterior teeth and the supporting structures (periodontal ligament and alveolar bone) were generated as a standard model based on a dental(More)
Myeloid-derived suppressor cells (MDSCs) accumulate in cancer patients and tumor-bearing mice, subsequently suppressing the host immune system. MDSCs represent a group of immature myeloid cells expressing CD11b and Gr-1. Here, we show that a Toll-like receptor (TLR) agonist, resiquimod, which binds to TLR7 and TLR8, induces the differentiation of MDSCs into(More)
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