Learn More
The subchronic inhalation toxicity of silver nanoparticles was studied in Sprague-Dawley rats. Eight-week-old rats, weighing approximately 253.2 g (males) and 162.6 g (females), were divided into four groups (10 rats in each group): fresh-air control, low dose (0.6 x 10(6) particle/cm(3), 49 microg/m(3)), middle dose (1.4 x 10(6) particle/cm(3), 133(More)
BACKGROUND The antibacterial effect of silver nanoparticles has resulted in their extensive application in health, electronic, consumer, medicinal, pesticide, and home products; however, silver nanoparticles remain a controversial area of research with respect to their toxicity in biological and ecological systems. RESULTS This study tested the oral(More)
The antimicrobial activity of silver nanoparticles has resulted in their widespread use in many consumer products. However, despite the continuing increase in the population exposed to silver nanoparticles, the effects of prolonged exposure to silver nanoparticles have not been thoroughly determined. Accordingly, this study attempted to investigate the(More)
BACKGROUND Gold nanoparticles are widely used in consumer products, including cosmetics, food packaging, beverages, toothpaste, automobiles, and lubricants. With this increase in consumer products containing gold nanoparticles, the potential for worker exposure to gold nanoparticles will also increase. Only a few studies have produced data on the in vivo(More)
Delayed gastrointestinal (GI) motility is frequent adverse effect associated with chemotherapy due to oxidative stress, activation of 5-HT3 receptors or serotonin releases from enterochromaffin cells. Fucoidan, extracts from brown seaweeds, has been showed antioxidant related favorable pharmacological activities including digestive tract protective effects.(More)
We compared the sleep quality indices between patients with mild cognitive impairment (MCI) and normal elderly subjects and analyzed the effects of sleep characteristics on cognitive functions. Cases of MCI patients (320 persons, MCI group) and 630 normal elderly with matched age, gender, and level of education (control group) were enrolled in this study.(More)
Fucoidan extracts from brown seaweed have anticoagulant, antithrombotic, and antiviral activities. Low molecular weight fucoidan (LMF) obtained by acid hydrolysis of high molecular weight fucoidan showed more favorable bioactivity. Despite extensive work on LMF bioactivities, detailed studies on the genotoxicity of LMF have not been conducted. As part of a(More)
Warming winter and atmospheric nitrogen (N) deposition are expected to have effects on net primary production (NPP) of Chinese fir (Cunninghamia lanceolata) plantation and implications for plantation carbon sequestration. The effects of nongrowing-season warming on plant morphological and physiological traits were investigated in a greenhouse experiment(More)
We examined changes in expression of the candidate plasticity-related gene 15 (CPG15) in the dentate gyrus (DG) and hippocampal CA3 region in the pentylenetetrazole (PTZ) kindling model and investigated the role of this gene in the phenomenon of mossy fiber sprouting (MFS). Experimental rats were divided into the control and PTZ groups. The epileptic model(More)
  • 1