Monique R. Anderson

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Plasmalemmal neurotransmitter transporters (NTTs) regulate the level of neurotransmitters, such as dopamine (DA) and glutamate, after their release at brain synapses. Stimuli including protein kinase C (PKC) activation can lead to the internalization of some NTTs and a reduction in neurotransmitter clearance capacity. We found that the protein Flotillin-1(More)
BACKGROUND The vagus nerve descends from the brain to the gut during fetal life to reach specific targets in the bowel wall. Vagal sensory axons have been shown to respond to the axon guidance molecule netrin and to its receptor, deleted in colorectal cancer (DCC). As there are regions of the gut wall into which vagal axons do and do not extend, it is(More)
HTLV-1 is a human retrovirus that is associated with the neuroinflammatory disorder HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). In these patients, HTLV-1 is primarily found in the CD4+CD25+ T cell subset (Regulatory T cells:Tregs), which is responsible for peripheral immune tolerance and is known to be dysfunctional in HAM/TSP.(More)
During fetal life, vagal sensory fibers establish a reproducible distribution in the gut that includes an association with myenteric ganglia. Previous work has shown that netrin is expressed in the bowel wall and, by acting on its receptor, deleted in colorectal cancer (DCC), mediates the guidance of vagal sensory axons to the developing gut. Because the(More)
HTLV-1 is a human retrovirus that is associated with adult T-cell leukemia/ lymphoma (ATLL) as well as the neu-roinflammatory disorder HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP). In these patients, HTLV-1 is primarily found in the CD4+CD25+ T cell subset (Regulatory T cells or Tregs), the cells that are responsible for peripheral(More)
Viruses have evolved many mechanisms by which to evade and subvert the immune system to ensure survival and persistence. However, for each method undertaken by the immune system for pathogen removal, there is a counteracting mechanism utilized by pathogens. The new and emerging role of microvesicles in immune intercellular communication and function is no(More)
The MHC class I D(k) molecule supplies vital host resistance during murine cytomegalovirus (MCMV) infection. Natural killer (NK) cells expressing the Ly49G2 inhibitory receptor, which specifically binds D(k), are required to control viral spread. The extent of D(k)-dependent host resistance, however, differs significantly amongst related strains of mice,(More)
Even though HIV does not infect neurons, extracellular Tat is internalized by neurons, localizes to the nucleus and can interact with numerous neuronal proteins to impact a variety of cellular processes. The serine/threonine-protein phosphatase PP1 (PP1) is among the numerous host proteins to which Tat can bind. PP1-alpha contributes to the regulation of(More)
  • David Anderson, Monique Anderson, Asa Bishop, Mary Dale Blanton, Tom George, Fred Gilliam +35 others
  • 1999
Julian called the meeting to order at 1:30 p.m. I. Announcements Julian presented information on the Standing Committee on General Education. The charge to the committee and its membership are found on page 12249. Tober announced a Web site is being set up for Undergraduate Council. Members will be notified of the address as soon as the site is ready for(More)
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