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PURPOSE Dysfunctions of auditory-verbal declarative and working memory are observed in patients with depressive disorders (DD). The authors wanted to see, whether antidepressive therapy improved the efficiency of cognitive processes among patients suffering from DD and determine possible associations between auditory-verbal declarative and working memory(More)
BACKGROUND Depressive disorder (DD), including recurrent DD (rDD), is a severe psychological disease, which affects a large percentage of the world population. Although pathogenesis of the disease is not known, a growing body of evidence shows that inflammation together with oxidative stress may contribute to development of DD. Since reactive oxygen species(More)
Autobiographical memory (AM) is a ubiquitous human experience that belongs to long-term declarative memory. It plays interpersonal and intrapsychic functions. The main aim of this study is to present results of contemporary research on AM in recurrent depressive disorders. The available research literature suggests that AM dysfunctions are a precursor and(More)
BACKGROUND 50% to 60% of the people who have recovered from the first episode of depression experience a relapse. The immune system of the people suffering from depression is in a permanent state of pathological pro-inflammatory readiness. There are some reports that depressive episodes cause sensitization of immune-inflammatory pathways and that staing of(More)
BACKGROUND/AIM Depressive disorders are multifactorial diseases, in which cognitive impairment is one of the characteristic feature. One of the molecules that regulate of various cognitive, emotional and behavioural processes is nitric oxide (NO), synthesized from l-arginine by a family of isoformic enzymes known as nitric oxide synthases (NOS). NO is a(More)
Cyclooxygenase-2(COX-2) may be a key inflammatory enzyme involved in recurrent depressive disorder(rDD). In rDD group, COX-2 expression were higher and significant correlations occurred between COX-2 expression and cognitive functions. In controls there was no significant association between analysed variables. Thus, the COX-2 enzyme may be important for(More)
Affective disorders are one of the main causes of hospitalisation among women and men older than fifty years old. Yearly, about 100 million people all over the world disclose symptoms of depression. Although the most noticeable signs of this disease concern the emotional sphere, it can also significantly influence their cognitive functioning. Deterioration(More)
AIM Aim of this study was to evaluate the relationship between subjective evaluation of disease (the intensity of symptoms, complaints and nuisance effects of treatment) in selected skin diseases and digestive system and investigated psychological factors: the level of stress and severity of state anxiety and trait anxiety. METHOD Verification of the(More)
Affective disorders are one of the main causes of hospitalisation among women and men older than fifty years old. Yearly, about 100 million people all over the world disclose symptoms of depression. Although the most noticeable signs of this disease concern the emotional sphere, it can also significantly influence their cognitive functioning. Deterioration(More)
Depressive disorder is a multifactorial diseases, that one of the typical feature are cognitive impairments. The aim of this study was to determine the total antioxidant status (TAS) in patients with recurrent depressive disorder (rDD) and to define relationship between plasma levels of TAS and the cognitive performance. Design and methods: the study(More)