Monika Kamianowska

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The protective effect of erythropoietin (Epo) is based on its ability to reduce oxidation and to stabilize the cells. The aim of the study was to evaluate the influence of Epo on malonyl dialdehyde (MDA), intercellular adhesion molecule-1 (ICAM-1) (CD54) and platelet-endothelial cell adhesion molecule-1 (PECAM-1) (CD31) levels on human umbilical vein(More)
OBJECTIVE To determine the effects of fluorides on endothelial functioning. MATERIALS AND METHODS We analyzed expressions of adhesion molecules, ICAM-1 and ICAM-3, and annexin V, on the surface of human umbilical vein endothelial cells (HUVECs) exposed to various concentrations of NaF and SnF(2) . We compared the effects of fluoride-induced changes with(More)
UNLABELLED The human immune system recognize and eliminate strange antigens by present of lymphoid cell clones, which to come into being in consequence of clonal proliferation inducted by contact with the antigen. The cell clones to be due to the somatic mutations and recognize antigens incorrectly are eliminate by apoptosis. THE AIM OF THE STUDY To(More)
Background/aims: Hyperglycemia disturbs normal oxidation-reduction reaction of cells leading to the increase in generation of reactive oxygen species (ROS). Erythropoietin (EPO), a sensitive to hypoxia physiological erythropoiesis regulator, is described as a factor inhibiting cell oxidative stress. In the present study, we examined an effect of high(More)
UNLABELLED The latest research proved that erythropoietin (Epo), a sensitive to hypoxia physiological erythropoiesis regulator, used successfully to treat anemia, displays cytoprotective, angiogenic, anti-inflammatory, anti-oxidative and anti-apoptotic properties. The aim of the study was to examine the influence of Epo on intercellular adhesion molecule-1(More)
Cytoprotection can be defined as the ability to protect cells against wide variety of damaging agents. A series of recent studies indicate that many substances participate in this process. It has been proved that different mechanisms as inhibition of oxidative stress or apoptosis mediate in cytoprotection. However, a number of mechanisms responsible for(More)
UNLABELLED Hyperglicemia is recognised as a primal factor responsible for microcirculatory changes in diabetic patients. There exist many reasons to claim that high glucose concentrations, generating reactive oxygen species (ROS), induce oxidative stress which initiates peroxidation processes. The end products of lipids peroxidation (aldehydes) cause(More)
UNLABELLED According last research erythropoietin (Epo), glycoprotein known as a physiological regulator of erythropoiesis and used successfully to treat anemia, displays cytoprotective properties. It is supposed that the protective effect of EPO is based on its ability to oxidation-reduction stabilization of cells. AIM The aim of the study was to examine(More)
UNLABELLED Neutrophil gelatinase-associated lipocalin (NGAL) is one of the most extensively examined biological markers for early prediction of acute kidney injury, but there is a lack of data on normal NGAL values in healthy term-born infants. This encouraged us to established serum and urine levels using samples collected from 38 girls and 50 boys, born(More)
Objective:The aim of work was to establish the normal levels of serum and urinary kidney injury molecule-1 (sKIM-1 and uKIM-1) in healthy full-term newborns.Study Design:The study included 88 healthy full-term neonates from normal, uncomplicated pregnancies. The serum and urinary concentrations of KIM-1 in the material obtained in the first or second day of(More)
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