Monika Jedynak

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PURPOSE Necrotizing fasciitis (NF) is a rare, life-threatening soft-tissue infection, characterized by rapidly spreading inflammation, with secondary necrosis of the fascia and surrounding tissues. It is mostly caused by group A beta-haemolytic streptococci or multibacterial. A case of the 25-year-old man admitted on September 2006 to the Department of(More)
Despite new generations of antibiotics and great improvement in the fields of rescue and modern intensive care medicine, sepsis remains one of the most frequent causes of complications and death in severely injured patients. Shock, bacterial colonization, invasive methods of treatment and immune mechanisms are reported to be responsible for the increased(More)
The diagnosis of acute pancreatitis (AP) is usually confirmed by a significant increase of the serum amylase and/or lipase level. However, serum pancreatic elastase-1 (pEla-1) was found to be a more sensitive diagnostic marker in AP, when assayed by the radioimmunoassay procedure. We analyzed the serum concentration of pEla-1, measured by the ELISA(More)
Abdominal aortic aneurysm surgery (AAA) is associated with perturbations of immune response and decreased immunity to infection, followed by high risk of organ and systemic complications development, including sepsis. The postoperative mortality in patients with AAA comes up to 10-12% and determines us to look for factors that may influence the immune(More)
Many studies show important disturbances in hormonal balance in patients with severe sepsis. There are a lot of factors, which are involved in this process but the role of sex steroid hormones is unknown; especially, the role of testosterone, which is one of the anabolic hormones and a immune function modulator. We hope that sex steroid hormone mechanisms(More)
INTRODUCTION High postoperative mortality in patients undergoing aortic abdominal aneurysm (AAA) repair is predominantly associated with ischemia and reperfusion organ injury followed by multiple organ dysfunction syndrome (MODS). Experimental studies have shown a role of growth-related oncogene a (GROa) chemokine in mediating organ damage during(More)
UNLABELLED Septic shock is the reason of human body organs dysfunctions including the hormonal system. There are abnormal thyroid hormones releasing as well. It is also noticed that sepsis caused serious disturbances in pituitary-thyroid axis functions. This is called euthyroid sick syndrom - (ESS). THE AIM To qualify the prognostic value of thyroid(More)
INTRODUCTION Surgical trauma is associated with depression of the immune system, which results in a high complication rate following abdominal aortic aneurysm (AAA) repair. Monocyte chemotactic protein-1 (MCP-1) and regulated-on-activation normal T cell expressed and secreted (RANTES) protein are important mediators of the immune and inflammatory response.(More)
Among the patients admitted to the Intensive Care Unit there frequently occur disturbances of the upper gastrointestinal tract. They can be found as stress ulcerations which in turn may lead to bleeding. The high incidence of stress ulcers and bleedings from the upper gastrointestinal tract is associated with disturbances of gastric acid secretion, an(More)