Monika Gupta

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BACKGROUND Pregabalin is a potent ligand for alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which exhibits potent anticonvulsant, analgesic and anxiolytic activity. The pharmacological activity of pregabalin is similar to that of gabapentin and shows possible advantages. Although it shows analgesic efficacy against(More)
AIMS To study the effect of intravenous magnesium sulfate infusion on clinical outcome of patients of acute stroke. MATERIALS AND METHODS Sixty consecutive cases of acute ischemic stroke hospitalised within 24 h of an episode of stroke were taken as subjects. All subjects underwent a computed tomography head, and those found to have evidence of(More)
A simple, efficient and environment-friendly procedure is developed for the synthesis of 1-substituted-8-aryl-3-alkyl/aryl-4H-pyrazolo[4,5-f][1,2,4]triazolo[4,3-b][1,2,4]triazepines in the presence of N,N-dimethylformamide as an energy transfer medium, p-TsOH as catalyst and basic alumina as solid support under microwave irradiation. The products are(More)
OBJECTIVES Of this in vivo study was to evaluate various space maintainers in terms of survival rate, gingival health and presence of caries. DESIGN A total of 60 extraction sites in the age group of 4 to 9 years were divided into four groups and different space maintainers were placed in them viz (conventional band and loop, prefabricated band with(More)
BACKGROUND Regional anticoagulation with trisodium citrate for continuous venovenous hemodiafiltration (CVVHDF) is an effective and safe alternative to heparin, especially in patients at high risk for bleeding. However, regional citrate anticoagulation is not used widely because current protocols are complex, labor intensive, and cumbersome. Existing(More)
PURPOSE The present study was conducted to provide an overall perspective on the diagnosis of condylar fractures, to analyze the technique and results of different treatment methods used, and to evolve a protocol for the selection of an appropriate treatment modality for an individual case. PATIENTS AND METHODS A total of 28 patients with a condylar(More)
PURPOSE To grade nuclear cataracts using the Lens Opacity Classification System III (LOCS III) and the correlation with maximum nuclear density on Scheimpflug imaging and phacoemulsification parameters. SETTING Tertiary care center. DESIGN Longitudinal interventional study. METHODS The nuclear density of significant age-related cataracts was evaluated(More)
SUMMARY Sixty ASA grade I & II adult patients of either sex were randomly assigned into two groups. Group I (n=30) for I-gel and Group P (n=30) for LMA - ProSeal. We assessed the airway sealing pressure, ease of insertion, success rate of insertion, ease of gastric tube placement, airway trauma by post operative blood staining of the device, tongue, lip and(More)