Monica Tavares Barbosa

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CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited activity against established tumors. We demonstrated that CD25 expression is largely restricted to tumor-infiltrating Treg cells in mice and humans. While existing anti-CD25(More)
Due to certain specificities in the HIV epidemic, its spread has escaped the random transmission pattern of other infectious diseases. Observation of the epidemic has shown that individual behavior - relational patterns among individuals - plays a crucial role in HIV transmission and that strategies to prevent the epidemic's spread should take this factor(More)
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