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The Protégé project has come a long way since Mark Musen first built the Protégé metatool for knowledge-based systems in 1987. The original tool was a small application, aimed at building knowledge-acquisition tools for a few specialized programs in medical planning. From this initial tool, the Protégé system has evolved into a durable, exten-sible platform(More)
B ecause we can process only a tiny fraction of information available on the Web, we must turn to machines for help in processing and analyzing its contents. With current technology, machines cannot understand and interpret the meaning of the information in natural-language form, which is how most Web information is represented today. We need a Semantic Web(More)
Protégé-2000 is an open-source tool that assists users in the construction of large electronic knowledge bases. It has an intuitive user interface that enables developers to create and edit domain ontologies. Numerous plugins provide alternative visualization mechanisms, enable management of multiple ontologies, allow the use of interference engines and(More)
Problem-solving methods provide reusable architectures and components for implementing the reasoning part of knowledge-based systems. The Unified Problem-Solving Method Description Language (UPML) has been developed to describe and implement such architectures and components to facilitate their semi-automatic reuse and adaptation. In a nutshell, UPML is a(More)
Problem-solving methods are ready-made software components that can be assembled with domain knowledge bases to create application systems. On-tologies and problem-solving methods have a long history of intricate relationships. In this chapter, we describe these relationships and how they can be used in a principled manner to construct knowledge systems. We(More)
During the past decade, there has been increasing consensus within the knowledge-based–systems community on appropriate conceptual components for building intelligent computer programs. Intelligent systems are now generally construed in terms of both domain ontologies and abstract problem-solving methods that operate on knowledge bases defined in terms of(More)
In recent years, public health surveillance has become a priority, driven by concerns of possible bioterrorist attacks and disease outbreaks. Authorities argue that syndromic surveillance, or the monitoring of prediagnostic health-related data for early detection of nascent outbreaks, is crucial to preventing massive illness and death. Syndromic(More)
This article describes a case study in which Protégé-2000 was used to build a tool for constructing CommonKADS knowledge models. The case study tries to capitalize on the strong points of both approaches in the tool-support and modeling areas. We specify the CommonKADS knowledge model as an ontol-ogy in the Protégé specification formalism, and define a(More)
A medical terminological system (TS) is essentially an ontology consisting of concepts, attributes and relationships pertaining to medical terms. There are many TSs around today, most of which are essentially frame-based. Various efforts have been made to get a better understanding of the requirements and the conceptual and formal structures of TSs.(More)